This study is predicated upon Mr. Li Yining's inaugural academic monograph in economics, along with five representative scholarly works, with the objective of delving into the distinctive methodological that characterize his economic research. It elucidates Mr. Li's philosophical stance, firmly rooted in Marxist practice, which serves as the cornerstone of his economic thought. Furthermore, it highlights his remarkable methodological traits, such as prioritizing institutions, integrating historical analysis with theoretical discourse, drawing from both Eastern and Western intellectual traditions, and deriving arguments from historical contexts. The emphasis on institutions and the integration of historical analysis constitute fundamental attributes of Mr. Li Yining's economic methodology. His scholarly pursuits embody a spirit that transcends cultural confines while accentuating practical innovation. The healthy advancement of contemporary Chinese economics, along with theories pertaining to economics and management, necessitates an ardent promotion of the distinctive qualities inherent in Mr. Li's economic methodology. Furthermore, leveraging his poetry can illuminate the four realms of knowledge and unveil their profound guiding power influence on intellectual endeavors.