Cultivating innovative talent that aligned with the demands of economic and social advancement presented a critical chal lenge for higher education institutions. The integration of industry-education and science-education provided profound insights for the cultivation of innovative talent within local application-oriented universities. By performing a comprehensive analysis of the positioning of application-oriented undergraduate talent cultivation the inherent characteristics of innovative talents and the demands of regional industrial development a clear model for the cultivation of application-oriented undergraduate innovative talent were meticulously es tablished. Starting with the transformation of organizational operational mechanisms the establishment of diversified guidance teams and the expansion of multimodal educational platforms this paper delved into a pioneering model for cultivating application-oriented undergraduate innovative talent which was propelled by multi-stakeholder collaboration among government entities academic institu tions local communities and enterprises. This approach promoted the profound integration of industry science and education there by achieving the established objectives of application-oriented undergraduate innovative talent cultivation. Additionally it addressed the diverse societal demands for high quality professionals.