Amidst the transformation and upgrade of traditional trade, the State Council has progressively established cross-border e-commerce comprehensive pilot areas, significantly impacting the agglomeration of productive service industries.Utilizing a multi-phase double difference model for empirical analysis, the study finds that these policies notably enhance both the specialized and diversified agglomeration of urban productive service industries. This enhancement is achieved by elevating the level of openness, information technology, and stimulating innovation effects. Furthermore, the policy's impact varies by city level and region, with more pronounced effects in provincial capitals, sub-provincial cities, and particularly in eastern regions. Hence, to foster the agglomeration of productive service industries and boost manufacturing productivity, it is vital to continuously increase the level of openness, leverage information technology, foster an innovative environment, and tailor the policies to local specifics.