New Era Civilization Practice Center is a platform for further improving propaganda, ideological and cultural work and spiritual civilization construction at grass-root level in rural area. In order to explain the internal mechanism and important conditions of spiritual civilization construction, this paper reviews and summarizes the representative actions of civilization construction in China, and puts forward a theoretical explanation framework for “civilization” . The main conditions of “civilization” actions are: ( 1) to conform to the civilization process of the times and put forward the content of civilization construction; ( 2) to play the important role of social network in civilization; ( 3) to focus on the simultaneous changes of the psychological structure and social structure of the grassroots groups; ( 4) to achieve civilization in the process of improving the income level of the grass-root groups. Based on this understanding, this paper analyzes the main progress and effect of Jiangning New Era Civilization Practice Center, raises the existing main problems and offers some suggestions for future improvement.